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Brlhan wist Jcl GALAS

Jcl:ICR – Nomura Siam International

Only a few reports have shown spontaneous occurrence of this tumor in the spinal cord, and no report has mentioned its occurrence in young rats. We encountered a case of spontaneous oligodendroglioma in the lumbar portion of the spinal cord in a young (9 weeks old) female BrlHan:WIST@Jcl (GALAS) rat BrlHan:WIST@Jcl(GALAS) rats also have a slightly smaller litter size than the SD rat (Aoyama et al . 2002; Fujii et al . 2002). In contrast to these findings, it was reported that the pregnancy rate and litter size in Tac:Glx:WifBR rats, another stock of WH rats, was lower than SD rats, and the incidences of implantation loss and fetal malformations were higher ( Liberati et al . 2002 ) Vacuolar Change in the Thyroid Follicular Cells in BrlHan : WIST@Jcl (GALAS) Rats SHIMOI Akihito , KUWAYAMA Chitose , MIYAUCHI Makoto , KAKINUMA Chihaya , KAMIYA Masatsugu , HARADA Tsuyoshi , OGIHARA Takuo , KUROKAWA Misao , MIZUGUCHI Kiyoshi Journal of toxicologic pathology 14(3), 253-257, 2001-09-3 BrlHan:WIST@Jcl (GALAS), Jcl:SD BrlHan:WIST@Jcl (GALAS), Jcl:SD NOV DEC JUN DATE MAR APR MAY SEP OCT DATE AUG FEB JAN JUL. Author: USER Created Date: 11/14/2018 7:18:01 PM. Estrous Stage- and Animal Age-Independent Superovulation in the BrlHan:WIST@Jcl(GALAS) Rat. Yusuke SOTOMARU 1), Tsutomu KAMISAKO 2), Kyoji HIOKI 1) 1) Central Institute for Experimental Animals 2) JAC Inc. Released 2005/05/17.

A Spontaneous Oligodendroglioma in the Lumbar Portion of

BrlHan:WIST@Jcl (GALAS) rat. Four-week-old BrlHan:WIST@Jcl (GALAS) rats (36 animals of each sex) were purchased from Charles River Laboratories Japan, Inc. (Shiga, Japan), for a toxicity study and housed in suspended aluminum cages (one rat per cage) in a room kept at 24 ± 2 °C and 40-70% RH with a 12-h light/dark cycle Galas, A. Grodzicki, T. Zawisza, K. Tobiasz-Adamczyk, B. Download Collect. Pancreatic Ductal Adenocarcinoma in a Wistar Hannover GALAS Rat. Kuroda, Yusuke Hayashi, Seigo Hagio, Soichiro Abe, Masayoshi Furukawa, Satoshi Nakae, Dai There are no reported spontaneous cases of pancreatic ductal adenocarcinoma (PDAC), and there are few reports about.

In this group, 6-week-old male Wistar Hannover GALAS rats (BrlHan:WIST@Jcl, GALAS) (CLEA Japan, Inc., Tokyo, Japan) were subjected to combined treatment with 5 carcinogens targeting different organs: a single intraperitoneal injection of 100 mg/kg body weight of N -nitrosodiethylamine at commencement, 4 intraperitoneal injections of 20 mg/kg body weight of N -methylnitrosourea (MNU) during the. The animal was a 10-week-old female GALAS rat (BrlHan:WIST@jcl, purchased from CLEA Japan, Inc., Tokyo, Japan) that was assigned to the control group in a 4-week repeated-dose oral toxicity study and subjected to the final sacrifice according to the experimental protocol

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Request PDF | Morphological and Endocrinological Characteristics of the Endocrine Systems in Wistar Hannover GALAS Rats Showing Spontaneous Dwarfs | We found spontaneous dwarfs in Wistar Hannover. The BrlHan:WIST@Jcl(GALAS) rat was selected as the test animal for two reasons: its genetic and microbiological properties are known, and HanBrl:WIST is the species used in the 2-year bioassay of Metofluthrin. The animals were acclimated to laboratory conditions for 7 days prior to dosing (the age of animals was 9 weeks old) The affected animal was a specific pathogen-free female BrlHan:WIST@Jcl (GALAS) rat purchased at the age of 13 weeks from the Fuji Breeding Center (CLEA Japan, Inc., Hamamatsu, Japan) and housed in a barrier-sustained animal room at controlled temperature (22 ± 2°C), humidity (50 ± 20%), ventilation (at least 10 times/hr, on an all-fresh-air basis) and illumination (12 hr/day, light on at. (BrlHan: WIST@Jcl[GALAS]) rats of both sexes were pur-chased from Japan Clea, Inc. (Shizuoka, Japan). Two animals were housed in each suspended stainless steel cage in an air-conditioned animal room with a temperature, 22+ 3 C; humidity, 50 + 20%; ventilation for the circulation of fresh air, 10 times or more per hr; and illumination, 12 hr/day. female GALAS rat (BrlHan:WIST@jcl, purchased from CLEA Japan, Inc., Tokyo, Japan) that was assigned to the control group in a 4-week repeated-dose oral toxicity study and subjected to the final sacrifice according to the experi-mental protocol. During the treatment period, there was no abnormality in clinical signs or body weight of the animal

Differences in spontaneous fetal abnormalities among three

  1. In 2003, 2 dwarf pups (same litter) were found in a colony of Wistar Hannover GALAS (BrlHan:WIST@Jcl [GALAS]) rats (Japan CLEA). A dwarf male rat and normal female were mated (sib mating) as founder, and sib mating was performed afterward. Strain characteristic
  2. • Sprague-Dawley (Crl:CD(SD)) and Wistar Hannover (RccHan:WIST and BrlHan:WIST@Jcl(GALAS)) were used. Thoracolumbar supernumerary ribs (TSR) 5 • Classified as a variation. • Relatively high incidence observed in a rodent study. • Researchers' opinions split on the significance of TSR
  3. BrlHan:WIST@Jcl(GALAS) Rats-Koji USUDA, Masayoshi ABE, Rie KUBOTA, and Satoshi FURUKAWA..... 6. Background Data of Blood Chemistry Parameters in Toxicity Studies Using Crj:CD(SD)IGS Rats at 10, 19 and 32 Weeks of age-Kazuhisa HATAYAMA.
  4. Corresponding Author. A Study Group for Historical Control Data on Prenatal Developmental Toxicity Studies in Rodents. Correspondence: Makoto Ema, DVM, PhD, Research Institute of Science for Safety and Sustainability, National Institute of Advanced Industrial Science and Technology (AIST), 16‐1 Onogawa, Tsukuba, Ibaraki 305‐8569, Japan
  5. BrlHan:WIST@Jcl (GALAS) Hannover Rat 仕入れ B.S SPF 供給動物 Jcl:SD SD 仕入れ B.S SPF 供給動物 Jcl:Wistar Wistar 仕入れ B.S SPF 供給動物 Crl:CD(SD) CD, SD, CD(SD), CD (IGS) 仕入れ B.S SPF 供給動物 Crlj:WI Wistar 仕入れ B.S SPF 供給動物 Crlj:LE LE, Long Evans 仕入れ B.S SPF 供給動
  6. • Sprague-Dawley (Crl:CD(SD)) and Wistar Hannover (RccHan:WIST and BrlHan:WIST@Jcl(GALAS)) were used. 5 Today's talk •Using CT scanning, monitor TSR morphological changes after birth in the same animal. 5-FC induced TSR rat model (postnatal observation) Chemical : 5-flucytocine (5-FC) Dose : 0, 35 or 75 mg/kg.
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rats (BrlHan:WIST@Jcl, GALAS) (CLEA Japan, Inc., To-kyo, Japan) were subjected to combined treatment with 5 carcinogens targeting different organs: a single intraperi-toneal injection of 100 mg/kg body weight of N-nitrosodi-ethylamine at commencement, 4 intraperitoneal injection BrlHan:WIST@Jcl(GALAS) rat. Exp Anim 2005 Apr;54(2):137-41. Central Institute for Experimental Animals, Kanagawa, Japan BrlHan:WIST@Jcl(GALAS) ウズラ成鶉 ウズラ種卵 種卵 Kud:ddY Sea:ddY Sea:ICR C57BL/6JSlc-gld/gld Std:JW/CSK(日本白色種) Std:JW/CSK(日本白色種) JW B.S Conv Conv Kbl:NZW Slc:NZW Slc:NZW Std:NZW Std:NZW Std:NZW NZW Crl:MON(Tum) Mongoliangerbil Chinese Conv Slc:Syrian Slc:Syrian Slc:Syrian 【シリアンハムスター

Vol.30,No.2,2002 RATPULMONARYSEQUESTRATION 289 FIGURE1.—Cutsurfaceofthepulmonarycysticlesion. 2.5.FIGURE2.—Variably-sizedcystscontainingmucusandin. Prior to the MOA analysis, BrlHan:WIST@Jcl(GALAS) (Wistar strain) rats aged 4 weeks were purchased from CLEA Japan, Inc., Fuji Breeding Center (Shizuoka, Japan) and used in the toxicity screening study at the early stage of development of this chemical; liver samples from the BrlHan:WIST@Jcl(GALAS) rats were subjected to the global gene expression profile analysis and the data are presented in.

Vacuolar Change in the Thyroid Follicular Cells in BrlHan

According to Shimoi et al., 8.5% (10/118) of Wistar Hannover GALAS rats obtained from CLEA Japan Inc. (BrlHan:WIST@Jcl[GALAS] rats) exhibited an enlargement of the thyroid gland [13] . Doi et al. further reported that the cross of externally normal BrlHan:WIST@Jcl[GALAS] rats yielded dwarf offspring with low serum T3 and T4 levels accompanied by a high serum TSH level [12] other: BrlHan:WIST@Jcl[GALAS] Details on species / strain selection: The Wistar Hannover GALAS rat was selected because the rat is a commonly used mammalian species for reproduction toxicity studies of agricultural chemicals and because this strain of rats yields stable reproduction results ST: Wistar/ST, Han: BrlHan:WIST@Jcl (GALAS). A significant difference from Wistar/ST rats of the same sex is indicated by ss P < 0.01 and sss P < 0.001, Mann-Whitney U test. (D) Prevalence of unilateral thyroid dysgenesis compared between F0 and F1 litters from Wistar/ST rats with thyroid hemiagenesis

Vacuolar Change in the Thyroid Follicular Cells in BrlHan : WIST@Jcl (GALAS) Rat m n b g CWistar Hannover n [BrlHan:WIST@Jcl (GALAS)] C C110 T . m Տ Ǐ n Ǘ ́C2 N Ԕ ̔팱 ^ Q ̓ ŁC ^65 T ɍ 5 mm ̑傫 ̎ ᎂ ꂽ D Ǘ ɂ͎ ᎈȊO Ɉ ʏ Ԃُ̈ ͔F ߂ Ȃ Article Snippet: In this group, 6-week-old male Wistar Hannover GALAS rats (BrlHan:WIST@Jcl, GALAS) (CLEA Japan, Inc., Tokyo, Japan) were subjected to combined treatment with 5 carcinogens targeting different organs: a single intraperitoneal injection of 100 mg/kg body weight of N -nitrosodiethylamine at commencement, 4 intraperitoneal injections of 20 mg/kg body weight of N -methylnitrosourea.

  1. BrlHan:WIST@Jcl (GALAS) rat purchased at the age of 13 weeks from the Fuji Breeding Center (CLEA Japan, Inc., Hamamatsu, Japan) and housed in a barrier-sustained animal room at controlled temperature (22 ± 2°C), humidity (50 ± 20%), ventilation (at least 10 times/hr, on an all-fresh-ai
  2. al aorta
  3. In a flank region on either side of an eight-week-old BrlHan: WIST@Jcl (GALAS) rat (four rats used in each test group), a full-thickness skin incision wound with a size of 2.5 cm×2.5 cm was created
  4. Thyroid dysplasia was recognized in WistarHan GALAS rats and confirmed as a heritable congenital disorder. The gene or genes involved were not identified, but homozygous animals with thyroid dysplasia also exhibited stunted growth, had reduced pituitary gland growth hormone (GH) and were hypothyroid. Heterozygous animals exhibited thyroid dysplasia with normal thyroid hormonal homeostasis and.
  5. istered a potent thyroid peroxidase inhibitor, 3-a
  6. (2004). Morphological and endocrinological characteristics of the endocrine systems in Wistar Hannover GALAS rats showing spontaneous dwarfs. (2009). Thyroid dysplasia in Wistar Hannover GALAS Rats. (1988). Ultrastuctural aspects of the goiter in cog/cog mice. Vacuolar change in the thyroid follicular cells in BrlHan: WIST@Jcl (GALAS) rats

Estrous Stage- and Animal Age-Independent Superovulation

CiteSeerX - Document Details (Isaac Councill, Lee Giles, Pradeep Teregowda): Abstract: Carcinosarcomas are rare tumors in humans as well as rats and most commonly occur in the uterus. Recently, we observed a case of incidental carcinosarcoma of the uterus in a female Wistar Hannover GALAS [BrlHan:WIST@ Jcl (GALAS)] rat at 2 years of age Z ֓ x 17 N x { Z p ҋ ֓ x ё 31 b Appropriate dose of lipopolysaccharide on fever in Wistar rats (BrlHan:WIST@Jcl strain) Kanmanee Sukkasem, Nuntika Prommee, Arunporn Itharat, Krittiya Thisayakorn, Vichein Khueynok, Kanchana Sriyam, Darunee Pahusee. 28-31 Test animals Species: rat Strain: other: SPF Wistar Hannover, BrlHan:WIST@Jcl[GALAS] Sex: male/female Details on test animals and environmental conditions: TEST ANIMALS - Source: Fuji Breeding Centre, CLEA Japan, Inc. (Shizuoka, Japan) - Age at study initiation: (P) 5 weeks; (F1) app. 4 weeks - Weight at study initiation: (P) males: 146 - 168 g, females: 110 - 125 g; (F1) males: 98 - 109 g.

微生物検査成績

Vacuolar change in the thyroid follicular cells in BrlHan

  1. LAC, Chiang Mai University is University of Excellence Where Nature Nurtures Beautiful Intelligenc
  2. A Spontaneous Oligodendroglioma in the Lumbar Portion of the Spinal Cord in a Young BrlHan: WIST@Jcl (GALAS) Rat: 日本毒性病理学会: 2014: 2014年 日本毒性病理学会 JTP業績賞: Thyroid Hormone-disrupting Effects and the Amphibian Metamorphosis Assay: 日本毒性病理学会: 2013: 2013年度 化学工学論文集 優秀論文
  3. [雑誌論文] Estrous Stage- and Animal Age-Independent Superovulation in the BrlHan : WIST@Jcl(GALAS) Rat. 2005. [学会発表] Effects of treatment for induction of superovalation in Brl Han : Wist@Jcl(GALAS)rats 2004
  4. In addition to these organs, nasal cavity, trachea, aorta, pituitary, thyroids, parathyroids, Specific pathogen-free Wistar male and female rats salivary glands, tongue, esophagus, stomach, duode- [BrlHan: WIST@Jcl (GALAS)] at 5 weeks old of age num, jejunum, ileum, cecum, colon, rectum, pancreas, were obtained from Crea Japan (Hamamatsu, Japan) urinary bladder, epididymides, prostate.

Estrous stage- and animal age-independent superovulation

This is an Accepted Manuscript, which has been through the Royal Society of Chemistry peer review process and has been accepted for publication. Accepted Manuscripts are published online shortly after acceptance, before technical editing, formatting and proof reading The strains of rats were Wistar Hannover GALAS against sialodacryoadenitis virus (SDAV). For detection of antibod- (BrlHan:WIST@Jcl), Fischer 344 (F344/N), Goto-Kakizaki (GK/Jcl) ies against M. pulmonis, M. pulmonis m53-infected BHK cells were and Spontaneously Diabetic Torii (SDT/Jcl) Berberine is an alkaloid extracted from medicinal plants such as Coptis chinensis and Phellodendron chinense . It possesses anti-inflammatory, anti-tumour and anti-oxidation properties, and regulates Glc and lipid metabolism Iron loading impairs lipoprotein lipase activity and promotes hypertriglyceridemia . FASEB J 27 : 1657 - 1663 , 2013 . OpenUrl Abstract / FREE Full Text 33. ↵ Yasuyuki M , Kazumoto S Koji U , Masayoshi A , Rie K , Satoshi F . Comparison of hematology and blood chemistry parameters between Crj:CD(SD)IGS rats and BrlHan: WIST@Jcl (GALAS) rats

[Journal Article] Estrous Stage- and Animal Age-Independent Superovulation in the BrlHan : WIST@Jcl(GALAS) Rat. 2005. Author(s) Sotomaru Y. Journal Title. Exp Amin 54・2. Pages: 137-141 NAID. 10015525802 . Data Source. KAKENHI-PROJECT-1530014 Appropriate dose of lipopolysaccharide on fever in Wistar rats (BrlHan:WIST@Jcl (GALAS) strain) Kanmanee Sukkasem Angelica sinensis alleviated menopausal symptoms in physically senescent ovarian rats associated with estrogen elevation Krittiya Thisayakorn Interaction of curcumin with hepatic and renal organic cation transporter Sirima Soodvila

CiNii 論文 - A Spontaneous Oligodendroglioma in the Lumbar

Focal disturbed laminar architecture in cerebellar vermis was observed in 25 out of 100 (25%) males, and 25 out of 100 (25%) females of BrlHan: WIST@Jcl rats. The cortical molecular and granular layers were haphazardly distributed around the primary and/or secondary fissures. The stellate and basket cells positively stained with parvalbumin immunohistochemistry were observed exclusively in the. Male BrlHan:WIST@Jcl (GALAS) rats were given N-nitrosodiethylamine (DEN), N-methylnitrosourea (MNU), 1,2-dimethylhydrazine (DMH), N-butyl-N-(4-hydroxybutyl)nitrosamine (BBN) and 2,2′-dihydroxy-di-n-propylnitrosamine (DHPN) for a total multiple initiation period of 4 weeks (DMBDD treatment) Wistar Hannover (BrlHan: WIST@Jcl (GALAS); LOT No. A730502-40-30) rats of both sexes were obtained at the age of 5 weeks from Clear Co. (Japan). Animals were housed in plastic cages (3 rats/cage) with wood chips for bedding, and allowed to acclimate for 1 week, then divided by stratified randomization into 3 male and 3 female body weight-matched groups, each comprising 50 rats

Possible carcinogenic risks of copper gluconate and their

According to Shimoi et al., 8.5% (10/118) of Wistar Hannover GALAS rats obtained from CLEA Japan Inc. (BrlHan:[email protected][GALAS] rats) exhibited an enlargement of the thyroid gland . Doi et al. further reported that the cross of externally normal BrlHan: [email protected] [GALAS] rats yielded dwarf offspring with low serum T3 and T4 levels accompanied by a high serum TSH level [12] [雑誌論文] Estrous stage- and animal age-independent superovulation in the BrlHan : WIST@Jcl(GALAS) rat. 2005 著者名/発表者名 Yusuke Sotomaru, Tsutomu Kamisako, et al clea japan inc wistar rats Wistar Rats, supplied by clea japan inc, used in various techniques. Bioz Stars score: 92/100, based on 15 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and mor 4 induced fasted motor activity in the duodenum (10). On the other hand, des-acyl ghrelin had no effect on fed motor activity in either the antrum or duodenum; however, it did disrupt fasted moto

BrlHan:WIST@Jcl , Jcl:SD Jcl:ICR , BrlHan:WIST@Jcl , Jcl:SD C57BL/6NJcl , BALB/cAJcl , BALB/cAJcl-nu , GK/Jcl Schedule for JULY - DECEMBER 2017 Week-age table of MCBC animals. Author: USER Created Date: 7/7. The Research and Consulting Company Ltd (RCC) received 156 breeding pairs of the Wistar Hannover GALAS™ outbred model from Dr. Willy Heine of Zentralinstitut für Versuchstierzucht in Hannover Germany in 1989. The rats were derived by caesarean in 1989. Taconic received breeding stock from RCC in 1998 An object of the present invention is to provide an active ingredient for a wound healing agent that has high biocompatibility and an antimicrobial activity, as well as a wound healing accelerating activity, which can be applied to supply of a wound healing agent comprising a single active ingredient, which can be produced by a simple production process and production apparatus A single nucleotide polymorphism in thyroglobulin gene causes dwarfism and goiter in Wistar Hannover GALAS rats. Sato A., Aoyama H. Submitted (NOV-2011) Strain: BrlHan:WIST@Jcl and Jcl:.

Toggle navigation . J-STAGE hom Predictable and reproducible production of transgenic rats from a standardized input of egg donors and egg recipients is essential for routine rat model production. In the course of establishing a transgenic rat service, transgenic founders were produced from three transgenes in outbred Sprague-Dawley (SD) rats and four transgenes in inbred Fischer 344 (F344) rats Chihaya Kakinuma, Toxicology Laboratory, Research Center, Mochida Pharmaceutical Co., Ltd., 342 Gensuke, Fujieda, Shizuoka 426-8640, Japan, undefined.. Laboratory Animal Center Chiang Mai University. 155 Moo.2 Tambon Mae Hia, Muang. Chiang Mai, Thailand. 50100. Telephone: 053-948621. FAX: 053-948630. E-mail: laccmu.

Galas, A. onAcademi

  1. 5-weeks-old female rats (BrlHan:WIST strain@Jcl) were purchased from CLEA Japan, Inc.. The rats were observed and verified that their general physical states are normal, and then the animals were used for the test. The animals were kept in polycarbonate-cages (5 rats in a cage) at room temperature of 23±2℃, 12 hour-lighting a day
  2. A novel mutation in the thyroglobulin gene that causes goiter and dwarfism in Wistar Hannover GALAS rats Akira Sato a , Kuniya Abe b , Misako Yuzuriha b , Sakiko Fujii c , Naofumi Takahashi a , Hitoshi Hojo a , Shoji Teramoto a , Hiroaki Aoyama a,∗
  3. The incidence of neoplastic lesions (16.7% in males and 43.8% in females of dead or moribund sacrificed animals) was also markedly high compared to that of BrlHan:[email protected](GALAS) rat (3.9% in males, 2.1% in females, CLEA Japan, Inc. 2002) and RCCHan™:WIST, Wistar Hannover rat (4.3% in males, 2.7% in females, Harlan Laboratories Ltd.
  4. Carcinosarcomas are rare tumors in humans as well as rats and most commonly occur in the uterus. Recently, we observed a case of incidental carcinosarcoma of the uterus in a female Wistar Hannover GALAS [BrlHan:WIST@ Jcl (GALAS)] rat at 2 years of age
  5. Polymorphisms that have been proven to influence gene functions are called functional polymorphisms. It is significant to know the distribution of functional polymorphisms in the rat, widely used i..
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Male Wistar Hannover Galas Rats clea japan inc Bio

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Spontaneous Basal Cell Carcinoma of the Submandibular

  1. Morphological and Endocrinological Characteristics of the
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